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C8 HPLC Silica-based analytical columns

Available with particle sizes 3, 5 and 10 µm

C8 chromatography columns offer a lower degree of hydrophobic selectivity than C18 columns.
They feature a modified silica surface with a layer of eight-carbon-atom chains (octylsilane).
Compared with C18 columns, C8 has a shorter and less hydrophobic (water-rejecting) stationary phase

This results in:
  • Shorter retention times: analytes interact with the column for less time, resulting in faster separations
  • More suitable for moderately polar analytes: compounds with some polarity are able to effectively untangle themselves in the C8 labyrinth
  • Reduced tail peak: Sharper peaks in the resulting chromatogram, indicating cleaner separation
  • Long column life and good repeatability


C8  HPLC Columns - Particle size 3 µm

CodeParticle size (µm)

Column dimensions  Ø×L (mm)
AN/210/565/IT32,1×50
AN/211/06532,1×100
AN/211/56532,1×150
AN/460/56534,6×50
AN/461/06534,6×100
AN/461/56534,6×150
AN/462/06534,6×200
AN/462/56534,6×250


C8  HPLC Columns - Particle size 5 µm

CodeParticle size (µm)

Column dimensions  Ø×L (mm)
AN/211/57552,1×150
AN/212/57552,1×250
AN/461/07554,6×100
AN/461/575/IT54,6×150
AN/462/075/IT54,6×200
AN/462/575/IT54,6×250

C8  HPLC Columns - Particle size 10 µm

Code AN/462/580 Particle size 10 µm column size 4.6×250 mm


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